Sometimes I feel a bit bougie using an Oxford Comma, but that only makes it more appealing. For those who are unsure as to whether they want to adopt it, may I offer the following travesty as evidence in favour:
Now, I know God did have at least one child, but he hasn’t been around for some time (although he’s due back anytime now), and my understanding was that Ayn Rand died alone on welfare, but it turns out I could be completely wrong.
So there, dear reader, is my suggestion; use the Oxford Comma. It is easy, useful, and doesn’t cost you anything.